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  • One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke

    One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke

    May 13, 2016

    One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke
    Amarenco P, Lavallee PC, Labreuche J, Albers GW, Bornstein NM, Canhao P, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Molina C, Rothwell PM, Sissani L, Skoloudik D, Steg PG, …

    May 13, 2016

  • TLOs in Takayasu Arteritis

    TLOs in Takayasu Arteritis

    Apr 22, 2016

    Tertiary lymphoid organs in Takayasu Arteritis
    Clement M, Galy A, Bruneval P, Morvan M, Hyafil F, Benali K, Pasi N, Deschamps L, Pellenc Q, Papo T, Nicoletti A, Sacre K
    2016 • Frontiers Immunol • [pdf] Objective: The role of B cells in the …

    Apr 22, 2016

  • LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections

    LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections

    Feb 4, 2016

    LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections
    Guo D, Regalado ES, Gong L, Duan X, Santos-Cortez RL, Arnaud P, Ren Z, Cai B, Hostetler EM, Moran R, Liang D, Estrera AL, Safi HJ, Leal SM, Bamshad MJ, Shendure J, …

    Feb 4, 2016

  • Beneficial effect of reducing microvascular thrombosis

    Beneficial effect of reducing microvascular thrombosis

    Dec 2, 2015

    Alteplase Reduces Downstream Microvascular Thrombosis and Improves the Benefit of Large Artery Recanalization in Stroke
    Desilles JP, Loyau S, Syvannarath V, Gonzalez-Valcarcel J, Cantier M, Louedec L, Lapergue B, Amarenco P, Ajzenberg N, Jandrot-Perrus M, Michel JB, Ho-Tin-Noe B, Mazighi M
    2015 …

    Dec 2, 2015

  • Chemical heterogeneity of biodegradable polymers & surface energy

    Chemical heterogeneity of biodegradable polymers & surface energy

    Nov 18, 2015

    Effect of chemical heterogeneity of biodegradable polymers on surface energy: A static contact angle analysis of polyester model films
    Belibel R, Avramoglou T, Garcia A, Barbaud C, Moras L
    2015 • Mater. Sci. Eng C • [pdf]

    Biodegradable and bioassimilable poly((R,S)-3,3 dimethylmalic acid) (PDMMLA) …

    Nov 18, 2015

  • Translational Immunometabolism

    Translational Immunometabolism

    Sep 28, 2015

    The Cellular and Molecular Basis of Translational Immunometabolism
    Norata GD, Caligiuri G, Chavakis T, Matarese G, Netea MG, Nicoletti A, O’Neill LA, Marelli-Berg FM
    2015 • Immunity • [pdf]

    The immune response requires major changes to metabolic processes, and indeed, energy metabolism and functional activation are …

    Sep 28, 2015

  • Platelets GPVI binds to fibrin

    Platelets GPVI binds to fibrin

    Sep 18, 2015

    Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation
    Mammadova-Bach E, Ollivier V, Loyau S, Schaff M, Dumont B, Favier R, Freyburger G, Latger-Cannard V, Nieswandt B, Gachet C, Mangin PH, Jandrot-Perrus M
    2015 • Blood • [pdf]

    Fibrin, the coagulation end …

    Sep 18, 2015

  • Platelets seal neutrophil-induced vascular breaches

    Platelets seal neutrophil-induced vascular breaches

    Sep 15, 2015

    Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice
    Gros A, Syvannarath V, Lamrani L, Ollivier V, Loyau S, Goerge T, Nieswandt B, Jandrot-Perrus M, Ho-Tin-Noe B
    2015 • Blood • [pdf]

    Platelets protect vascular integrity during inflammation. Recent evidence …

    Sep 15, 2015

  • Nanomedicine as a strategy to fight thrombotic diseases

    Nanomedicine as a strategy to fight thrombotic diseases

    Jul 4, 2015

    Nanomedicine as a strategy to fight thrombotic diseases
    Varna M, Juenet M, Bayles R, Mazighi M, Chauvierre C, Letourneur D
    2015 • Future Sci OA • [pdf]

    This review highlights the preclinical and clinical research based on the use of nano- and micro-carriers in …

    Jul 4, 2015

  • Role of platelets in the pathogenesis of Influenza virus

    Role of platelets in the pathogenesis of Influenza virus

    Jun 2, 2015

    Platelet Activation and Aggregation Promote Lung Inflammation and Influenza Virus Pathogenesis
    Le VB, Schneider JG, Boergeling Y, Berri F, Ducatez M, Guerin JL, Adrian I, Errazuriz-Cerda E, Frasquilho S, Antunes L, Lina B, Bordet JC, Jandrot-Perrus M, Ludwig S, Riteau B
    2014 …

    Jun 2, 2015

  • Organ repair & Nanoparticles

    Organ repair & Nanoparticles

    May 11, 2015

    Organ Repair, Hemostasis, and In Vivo Bonding of Medical Devices by Aqueous Solutions of Nanoparticles
    Meddahi-Pelle A, Legrand A, Marcellan A, Louedec L, Letourneur D, Leibler L
    2014 • Angew Chem Int Ed Engl • [pdf] • Video

    Sutures are traumatic to soft …

    May 11, 2015

  • CD31 & immunogenic DCs

    CD31 & immunogenic DCs

    May 11, 2015

    CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cells
    Clement M, Fornasa G, Guedj K, Ben Mkaddem S, Gaston AT, Khallou-Laschet J, Morvan M, Nicoletti A, Caligiuri G
    2014 • Proc Natl Acad Sci USA • [pdf]

    CD31 is …

    May 11, 2015

  • Collagen & Platelet secretory phenotype

    Collagen & Platelet secretory phenotype

    May 11, 2015

    Collagen Can Selectively Trigger a Platelet Secretory Phenotype via Glycoprotein VI
    Ollivier V, Syvannarath V, Gros A, Butt A, Loyau S, Jandrot-Perrus M, Ho-Tin-Noe B
    2014 • PLoS One • [pdf]

    Platelets are not only central actors of hemostasis and thrombosis but also …

    May 11, 2015

  • PN-1 & Pulmonary Fibrosis

    PN-1 & Pulmonary Fibrosis

    May 11, 2015

    Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression
    Francois D, Venisse L, Marchal-Somme J, Jandrot-Perrus M, Crestani B, Arocas V, Bouton MC
    2014 • Lab Invest • [pdf]

    Idiopathic pulmonary fibrosis (IPF) is …

    May 11, 2015

  • Hemostatic disorders in JAK2(V617F) Tg mice

    Hemostatic disorders in JAK2(V617F) Tg mice

    May 10, 2015

    Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm
    Lamrani L, Lacout C, Ollivier V, Denis CV, Gardiner E, Ho Tin Noe B, Vainchenker W, Villeval JL, Jandrot-Perrus M
    2014 • Blood • [pdf]

    Thrombosis is common in patients suffering from myeloproliferative …

    May 10, 2015

  • CD31 in the immunological synapse

    CD31 in the immunological synapse

    May 10, 2015

    Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo
    Clement M, Fornasa G, Loyau S, Morvan M, Andreata F, Guedj K, Khallou-Laschet J, …

    May 10, 2015

  • Mutations in an ECM gene in TAAD

    Mutations in an ECM gene in TAAD

    May 10, 2015

    MFAP5 Loss-of-Function Mutations Underscore the Involvement of Matrix Alteration in the Pathogenesis of Familial Thoracic Aortic Aneurysms and Dissections
    Barbier M, Gross MS, Aubart M, Hanna N, Kessler K, Guo DC, Tosolini L, Ho-Tin-Noe B, Regalado E, Varret M, Abifadel M, …

    May 10, 2015

  • Control of B cells in atherosclerosis

    Control of B cells in atherosclerosis

    May 10, 2015

    Control of the Tfh-GC B Cell Axis by CD8+ Tregs Limits Atherosclerosis and Tertiary Lymphoid Organ Development
    Clement M, Guedj K, Andreata F, Morvan M, Bey L, Khallou-Laschet J, Gaston AT, Delbosc S, Alsac JM, Bruneval P, Deschildre C, Le Borgne …

    May 10, 2015

  • Antiplatelet therapy in ACS

    Antiplatelet therapy in ACS

    May 8, 2015

    Clinical evidence for oral antiplatelet therapy in acute coronary syndromes
    Wiviott SD, Steg PG
    2015 • Lancet • [pdf]

    Platelet-mediated thrombosis is a major pathophysiological mechanism that underlies acute coronary syndromes, and therefore, antiplatelet therapy is an important foundation in the treatment and prevention of recurrence of …

    May 8, 2015

  • Thrombi and neutrophils

    Thrombi and neutrophils

    May 7, 2015

    Thrombi and neutrophils
    Michel JB, Ho-Tin-Noé B
    2015 • Circ Res • [pdf] (Editorial to this paper)

    More than a century ago, in 1881, Bizzozero discovered platelets and their role in primary hemostasis. Since this founding study, it has been shown that, in addition to the scaffold of …

    May 7, 2015