Seminars

'Therapeutic repositioning of Selexipag to prevent acute cardiovascular events by targeting vascular smooth muscle cell-derived foam cells ?'

Chair: Nour DARWICH

Océane MORALES (team 1): ‘Impact of hypothermia on cardiac microvascular functions during sepsis’ ; Chair: Hichem BADJI

Ophélie CHAPELLIER (team 4) : 'Polyplex-mediated delivery of miRNA using a novel cationic polyester'

Gaelle MERHEB (team 5): 'Effects of Omega-3 on Human Coronary Vascular Tone Induced by Neurotransmitters'

Chair: Pierre GRES

Sofiane MOHAMMED (team 1): ‘Effect of temperature on the humoral immune response’

Pierre GRES (team 6): 'Role of protease nexine-1 in hemarthrosis, a major complication of hemophilia'

Chair: Zhipeng LI

''The role of protease nexin-1 (PN-1) in glomerulonephritis progression'. Chairman: Zhuo (André) HUANG

12h00: Richard AUSTIN “Caffeine reduces PCSK9 expression though its ability to regulate ER calcium/SREBP activation”

15h00: Richard AUSTIN “Role of the PCSK9-Q152H LOF variant in protection against liver injury and cardiometabolic disease”

15h20: Mathilde VARRET “The singular French PCSK9-p.Ser127Arg gain-of-function variant: A significant player in cholesterol levels from a 775-year-old common ancestor”

15h40: Mathilde VARRET “PCSK9 in SMC and atherosclerosis”

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16h20: Discussion Générale

'New methods to look at molecules in action in model lipid bilayers and living cells.' ; Chair: Pierre SARFATI

Carine BRADAI (éq 2); Onnicher BUDRASI (éq 4);  Tristan FRAU (éq 6); Thomas LEFEBVRE (éq 1); Berliana NOVIANITA (éq 4); Lilia ZEGHDOUDI (éq 4); Jury : Elisa PERELLI, Chloé DUJARDIN, Zhuo HUANG, Emilie VONNA.

Sinem GEDIK (éq 5); Morgane DE SOUSA (éq 2); Adeline DOS SANTOS (éq 4); Jérémie FARWATI (éq 5) ; Matthieu M MASSIP (éq 4); Marie LLUDRIGUEZ (éq 3); Anoura MAMADOU (éq 4); Victor QUENTIN (éq 5); Violaine ROCHE SABIDO (éq 4); Laura SADIK PREIRA (éq 6); Nicolas GROSHENRY (éq 5); Diane PENA (éq 3). Jury: Maelle JAN, Océane MORALES, Elliot LOPEZ, Pierre GRES.

“How Mfd -Mutation Frequency Decline- bacterial protein is an innovative weapon against anti microbial resistance”; Chair: Maelle JAN.

'When adaptation to mechanical stimuli goes wrong: Cerebral Cavernous Malformations, a disease of low flow blood vessels'. Chair: Clémence MAUPU.

‘Exploring the molecular mechanisms underlying rare forms of familial hypercholesterolemia: from genetic analysis to LDL catabolism study’. Chair: Changsheng (Léo) LI

‘Growth and study of tumor spheroids behavior in a biomimetic vascularized platform’. Chair: Ophélie CHAPELLIER.

'Exploring the Potential of Specialized Pro-Resolving Mediators in Pulmonary Hypertension: A New Insight to Vascular Tone modulation'. Chair: Elisa PERELLI.

"Heart Failure - the fault of failing lymphatics?"; Chair: Emilie VONNA

"MR-based molecular imaging: from diagnosis to therapy". Chair: Gaelle MERHEB

‘Non-coding RNAs in chronic kidney disease, anemia and cardiovascular disorders : new clues for therapy’

'Plasmonic Nanomaterials and Biomaterials for Therapeutic Applications'. Chair: Nour DARWICH

Orlane Cohen (team 2): ‘The role of tenascin-X in hereditary thoracic aortic aneurysms.’
Garance Ennesser (team 6): 'The role of thrombin in the pathogenesis of intracranial aneurysms.'
Marike Weber ( M2, team 1): 'Impact of oxidative stress on platelet biology and the pathogenesis of Glomerulonephritis'

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‘Hybrid particles for the physical targeted treatment of thrombotic diseases’

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