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  • Acticor continues on its path, crowned with success

    Acticor continues on its path, crowned with success

    Acticor Biotech winner of the Prix Galien Medstartup in the category “BEST COLLABORATION IN THE PHARMACEUTICAL OR BIOTECHNOLOGICAL INDUSTRY”,organized by …

    Nov 17, 2021

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  • Dr IZA YouTube channel

    Dr IZA YouTube channel

    If you don’t know the YouTube channel of Dr IZA, this is the perfect occasion to discover it: a new …

    Oct 13, 2021

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  • Prof Mikael MAZIGHI awarded the “Prix MFP des donateurs” from the Fondation de l’Avenir

    Prof Mikael MAZIGHI awarded the “Prix MFP des donateurs” from the Fondation de l’Avenir

    The winner of this prize is chosen by the donors of the Fondation de l’Avenir from among six high-quality projects.
    The …

    Aug 26, 2021

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  • Pr Marianne Abi Fadel awarded the Christophe Mérieux 2021 prize

    Pr Marianne Abi Fadel awarded the Christophe Mérieux 2021 prize

    Prof. Marianne Abi Fadel, Dean of the Faculty of Pharmacy at USJ and member of the UMRS1148 Team 2, received …

    May 18, 2021

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  • Rapport sur l’intégrité scientifique

    Rapport sur l’intégrité scientifique

    L’OPECST a mis en ligne ce jour un rapport sur l’intégrité scientifique de 134 pages.

    Ci-jointe, la synthèse de 4 pages …

    Mar 5, 2021

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  • Anne Pellé appointed in the “ordre national de la légion d’honneur au grade de chevalier”

    Anne Pellé appointed in the “ordre national de la légion d’honneur au grade de chevalier”

    We are proud to announce that Anne Pellé (Team 3) has been promoted and appointed in the “ordre national de …

    Jan 5, 2021

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  • Acticor Biotech Announces the Recruitment of the First Patient in its Phase 2 GARDEN Study in COVID-19-related ARDS

    Acticor Biotech Announces the Recruitment of the First Patient in its Phase 2 GARDEN Study in COVID-19-related ARDS

    – Approval of phase 2 GARDEN study in France and Brazil

    – GARDEN will enroll 60 patients hospitalized for COVID19

    – First …

    Dec 22, 2020

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  • 3 scientists of the LVTS in the 2020 Top 1% Highly Cited Researchers

    3 scientists of the LVTS in the 2020 Top 1% Highly Cited Researchers

    Dec 4, 2020

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  • Karen Aymonnier, laureate of the Bettencourt prize for young investigators

    Karen Aymonnier, laureate of the Bettencourt prize for young investigators

    Each year,the Fondation Bettencourt awards prizes for Postdoc training to young investigators. Among the 14 laureates of the 2020 edition, …

    Dec 3, 2020

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  • LVTS in Eur Heart J: “a Cardiovascular Research Centre of Excellence”

    LVTS in Eur Heart J: “a Cardiovascular Research Centre of Excellence”

    Our research unit is spotlighted in the last issue of the European Heart Journal.

    Read the full paper:

    Sep 1, 2020

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  • Paris’ Claude Bernard Prize winner: Philippe-Gabriel STEG

    Paris’ Claude Bernard Prize winner: Philippe-Gabriel STEG

    As part of its policy of supporting medical research, the City of Paris annually awards two Grand Prizes to eminent …

    Feb 27, 2020

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  • Tridek-one in the INSERM journal.

    Tridek-one in the INSERM journal.

    In issue 44 of the INSERM journal, an article is devoted to the Tridek-one startup whose 2 scientific co-founders are …

    Oct 1, 2019

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  • Immunometabolism in CVD

    Immunometabolism in CVD

    Giuseppina Caligiuri (Team 1) and Danilo Norata (University of Milan) present the content of a Cardiovascular Research spotlight issue focusing …

    Jul 9, 2019

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  • ISTH honors Martine Jandrot-Perrus amongst four other members with Esteemed Career Awards

    ISTH honors Martine Jandrot-Perrus amongst four other members with Esteemed Career Awards

    The ISTH honored Martine Jandrot-Perrus (Team 6) amongst four other members with the Esteemed Career Award at the ISTH 2019 …

    Jul 7, 2019

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  • Thierry Lhermitte and FRM representatives at the LVTS

    Thierry Lhermitte and FRM representatives at the LVTS

    Jun 12, 2019

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  • Tridek‐One raises € 3 million from Advent France Biotechnology and Advent Life Science

    Tridek‐One raises € 3 million from Advent France Biotechnology and Advent Life Science

    Jun 4, 2019

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  • Catherine Boileau awarded the grand prize of scientific recognition by the Queen of Belgium

    Catherine Boileau awarded the grand prize of scientific recognition by the Queen of Belgium

    Apr 27, 2019

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  • Création de l’Université de Paris

    Création de l’Université de Paris

    Le décret, en date du 20 mars 2019, portant création de l’Université de Paris est paru au Journal officiel de …

    Apr 5, 2019

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  • Prof. PG Steg: appointed “Vice President for Research” of the Executive Board of AP-HP

    Prof. PG Steg: appointed “Vice President for Research” of the Executive Board  of AP-HP

    Prof. Philippe Gabriel Steg (head of Team 5) has been appointed “Vice President for Research” of the Executive Board of the …

    Mar 5, 2019

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  • Discover the portrait of Catherine Boileau, leader of Team 2

    Discover the portrait of Catherine Boileau, leader of Team 2

    In the last issue of the Magazine Science&Santé of INSERM,  there is a portrait of Catherine Boileau (co-head of Team 2) …

    Dec 14, 2018

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  • miRNA Delivery by Nanosystems

    miRNA Delivery by Nanosystems

    miRNA Delivery by Nanosystems: State of the Art and Perspectives
    Moraes FC, Pichon C, Letourneur D, Chaubet F
    2021 •Pharmaceutics • [pdf]

    MicroRNAs (miRNAs) …

    Nov 9, 2021

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  • In vitro strategies to vascularize 3D physiologically relevant models

    In vitro strategies to vascularize 3D physiologically relevant models

    In vitro strategies to vascularize 3D physiologically relevant models
    Dellaquila A, Le Bao C, Letourneur D, Simon-Yarza T
    2021 •Adv Sci (Weigh) • …

    Aug 6, 2021

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  • Coronary stent CD31-mimetic coating

    Coronary stent CD31-mimetic coating

    Coronary stent CD31-mimetic coating favours endothelialization and reduces local inflammation and neointimal development in vivo
    Diaz-Rodriguez S, Rasser C, Mesnier J, …

    Feb 16, 2021

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  • CD31 Mimetic Coating Enhances Flow Diverting Stent Integration

    CD31 Mimetic Coating Enhances Flow Diverting Stent Integration

    CD31 Mimetic Coating Enhances Flow Diverting Stent Integration into the Arterial Wall Promoting Aneurysm Healing
    †Cortese J, †Rasser C, Even G, …

    Feb 13, 2021

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  • Chicken egg white a new ‘old biomaterial’

    Chicken egg white a new ‘old biomaterial’

    Chicken egg white: Hatching of a new old biomaterial
    Jalili-Firoozinezhad S, Filippi M, Mohabatpour F, Letourneur D, Scherberich A
    2020 • Materials …

    Dec 3, 2020

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  • Membranes for Guided Bone Regeneration

    Membranes for Guided Bone Regeneration

    Membranes for Guided Bone Regeneration: A Road from Bench to Bedside
    Aprile P, Letourneur D, Simon-Yarza T
    2020 • Adv Healthc Mater• …

    Oct 31, 2020

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  • MedTech Translation in Academia

    MedTech Translation in Academia

    Enabling MedTech Translation in Academia: Redefining Value Proposition with Updated Regulations
    Letourneur D, Joyce K, Chauvierre C, Bayon Y, Pandit A
    2020 …

    Oct 31, 2020

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  • Nanomedicine progress in thrombolytic therapy

    Nanomedicine progress in thrombolytic therapy

    Nanomedicine progress in thrombolytic therapy
    Zenych A, Fournier L, Chauvierre C
    2020 • Biomaterials • [pdf]

    Thrombotic occlusions of blood vessels are responsible for …

    Sep 29, 2020

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  • Human and Rodent Prostaglandin Receptors & Prostacyclin Receptor

    Human and Rodent Prostaglandin Receptors & Prostacyclin Receptor

    International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and …

    Sep 28, 2020

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  • Phylogenic determinants of cardiovascular frailty

    Phylogenic determinants of cardiovascular frailty

    Phylogenic determinants of cardiovascular frailty, focus on hemodynamics and arterial smooth muscle cells
    Michel JB
    2020 • Physiol Rev • [pdf] The evolution of …

    Aug 30, 2020

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  • CD31 as a Therapeutic Target in Atherosclerosis

    CD31 as a Therapeutic Target in Atherosclerosis

    CD31 as a Therapeutic Target in Atherosclerosis
    Caligiuri G
    2020 • Circulation Res • [pdf]

    The potential of CD31 as a therapeutic target in …

    Apr 23, 2020

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  • Cleaved CD31 as a target for in vivo molecular imaging of inflammation

    Cleaved CD31 as a target for in vivo molecular imaging of inflammation

    Cleaved CD31 as a target for in vivo molecular imaging of inflammation
    Vigne J, Bay S, Aid-Launais R, Pariscoat G, Rucher …

    Dec 20, 2019

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  • A Comparison of 2 LDL Cholesterol Targets after Ischemic Stroke

    A Comparison of 2 LDL Cholesterol Targets after Ischemic Stroke

    A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke
    Amarenco P, Kim JS, Labreuche J, Charles H, Abtan J, Bejot …

    Nov 22, 2019

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  • Targeting PN-1 to control bleeding in hemophilia

    Targeting PN-1 to control bleeding in hemophilia

    Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
    Aymonnier K, Kawecki C, Venisse L, …

    Nov 19, 2019

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  • Bronchodilation induced by PGE2 is impaired in Group-III pulmonary hypertension

    Bronchodilation induced by PGE2 is impaired in Group-III pulmonary hypertension

    Bronchodilation induced by PGE2 is impaired in Group-III pulmonary hypertension
    Ozen G, Benyahia C, Mani S, Boukais K, Silverstein AM, Bayles …

    Oct 2, 2019

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  • Ticagrelor in Patients with Stable Coronary Disease and Diabetes

    Ticagrelor in Patients with Stable Coronary Disease and Diabetes

    Ticagrelor in Patients with Stable Coronary Disease and Diabetes
    Steg PG, Bhatt DL, Simon T, Fox K, Mehta SR, Harrington RA, …

    Sep 3, 2019

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  • Mitigation of monocyte driven thrombosis on cobalt chrome surfaces by polyurethane coatings

    Mitigation of monocyte driven thrombosis on cobalt chrome surfaces by  polyurethane coatings

    Mitigation of monocyte driven thrombosis on cobalt chrome surfaces in contact with whole blood by thin film polar/hydrophobic/ionic polyurethane coatings
    Gossart …

    Jul 10, 2019

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  • Mechanotransduction, immunoregulation, and metabolic functions of CD31 in CVD

    Mechanotransduction, immunoregulation, and metabolic functions of CD31 in CVD

    Mechanotransduction, immunoregulation, and metabolic functions of CD31 in cardiovascular pathophysiology
    Caligiuri G
    2019 • Cardiovasc Res • [pdf] Biomechanical changes in the heart and …

    Jul 9, 2019

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  • Safety and Tolerability, PK, and PD of an Antiplatelet GPVI Fab

    Safety and Tolerability, PK, and PD of an Antiplatelet GPVI Fab

    Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab
    Voors-Pette C, Lebozec K, Dogterom P, Jullien …

    Jun 19, 2019

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  • Functionalized polymer microbubbles to target thrombus

    Functionalized polymer microbubbles to target thrombus

    Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus
    Li B, Aid-Launais R, Labour MN, Zenych …

    May 29, 2019

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The LVTS is an attractive center:

  • For Excellence in Research
  • For Education
  • For Industrial and clinical transfers

The LVTS UMRS1148 is organised to understand the physiological mechanisms by basic science approaches but also through large clinical trials, development of new diagnostic (markers and imaging) and new therapeutic/biomaterial strategies : identification of new targets, development of new molecules, validated by clinical trials.

The unit is organised into 6 collaborative teams affiliated to 3 different ITMO (National Institutes) PMN, Technologies for Health, Genetics, and to 2 Inserm scientific sections (CSS3 and CSS6).

More than 240 collaborators working together among which 119 have permanent positions.

  • 15 full time researchers
  • 77 university-hospital affiliated faculty
  • 24 permanent technical assistants and 8 non-permanent technical assistants
  • 36 PhD students
  • 14 postdoctoral fellows
  • 25 undergraduates

Our translational human and technological skills include clinical databases and assays, translational clinical investigations (carotid stenosis, aneurysms and dissections of the ascending aorta, Biocore), human tissue and cell biobanks, numerous experimental models of disease (transgenic mice, rats, rabbits), new methods in molecular and cell biology (proteomics, genetics & epigenetics, protein engineering, flow cytometry), chemistry of biopolymers, elaboration of biomaterials and nanosystems, and imaging technologies in small animals and in humans (Nuclear Imaging, Ultrasound and MRI).

Our Teams are hosted in 3 locations in the North of Paris: