Team 6: Hemostasis, Thrombo-Inflammation and Neurovascular Repair

Team leaders: Marie-Christine BOUTON & Nathalie KUBIS

Team 6 comprises X groups, each led by a principal investigator:

The team 6 projects are focused on hemostasis, thrombosis and vascular injury, but are also involved in developing therapeutic strategies for cerebral ischemia at the acute and at the chronic phase. We combine biochemical and cellular approaches, in vivo experimental models and clinical researches for translational application.

Recently, we have demonstrated that:

  • Protease Nexin-1 is a serine protease inhibitor with an important protective role in tissues
  • GPVI is a platelet receptor with a central role in the repairing functions of platelets
  • There are tight interactions between actors of hemostasis/thrombosis and of the immune system during stroke

We have also developed:

  • New imaging modalities for intracranial vascular studies
  • Innovative endovascular approaches for the treatment of intracranial vascular malformations

Our major common research themes are:

  • Theme 1: Coagulation disorders (haemophilia, thrombophilia…)
  • Theme 2: Thrombo-inflammation (Platelets/ Leucocytes/ proteases & antiproteases of coagulation)
  • Theme 3: Vascular injury (stroke, aneurysms)
Family name
First name
Position
Tel
Email
AJZENBERGNadinePUPH101.40.25.85.21nadine.ajzenberg@aphp.fr
AROCASVéroniqueCR01.40.25.75.32veronique.arocas@inserm.fr
BLANCRaphaelPHrblanc29@gmail.com
BONNINPhilippeMCUPHHCphilippe.bonnin@aphp.fr
BOULAFTALIYacineCR01.40.25.86.15yacine.boulaftali@inserm.fr
BOURRIENNEMarie-CharlotteDoctorantmarie.bourienne@inserm.fr
BOUTIGNYAlexandreM2alexandre.boutigny@gmail.com
BOUTONMarie-ChristineDR201.40.25.75.32marie-christine.bouton@inserm.fr
CHALGOUMIRymM2rym.chalghoumi@hotmail.fr
DE RAUCOURTEmmanuellePHemmanuelle.de-raucourt@aphp.fr
DESILLESJean-PhilippePHU01.40.25.86.01jpdesilles@gmail.com
DI MEGLIOLucasDoctorant01.40.25.86.01lucas.dimeglio@gmail.com
DUPONTSébastienIRsebastien.dupont@inserm.fr
FAILLEDorothéeMCUPH01.40.25.85.21dorothee.faille@aphp.fr
GAYJulietteM2juliette.gay@aphp.fr
HO-TIN-NOEBenoitCR01.40.25.86.03benoit.ho-tin-noe@inserm.fr
JADOUISoumayaDoctorantjadoui.soumaya@hotmail.fr
JANDROT-PERRUSMartineDREM01.40.25.75.31martine.jandrot-perrus@inserm.fr
KUBISNathaliePUPH101.49.95.80.88nathalie.kubis@aphp.fr
LE CHAPELAINOphélieDoctorantophelie.lechapelain@gmail.com
LEBASHéloisePOST-DOCheloise.lebas@inserm.fr
LOYAUStéphaneIE01.40.25.75.33stephane.loyau@inserm.fr
LOZERONPierreMCUPH1pierre.lozeron@aphp.fr
MADJENECélinaDoctorant01.40.25.75.33celina.madjene@inserm.fr
MARTOSRaphaelDoctorantraphael.martos@inserm.fr
MAUPUClemenceM2maupu.clemence@gmail.com
MAZIGHIMikaelPUPH01.40.25.70.33mikael.mazighi@aphp.fr
MOUAZANSarahM2sarah_mouazan@hotmail.com
NOBRECatlineTCHcatline.nobre@inserm.fr
OLIVIEROceaneM2oceane-olivier@wanadoo.fr
OLLIVIERVéroniqueIE01.40.25.86.03veronique.ollivier@inserm.fr
PIOTINMichelPHUmpiotin@for.paris
RICHARDBenjaminMCF01.40.25.86.15benjamin.richard@inserm.fr
SOLO NOMENJANAHARYMialitianaAI01.40.25.86.01mialitiana.solo-nomenjanahary@inserm.fr
SONNEVILLERomainPUPH01.40.25.61.39romain.sonneville@aphp.fr
TUALNolanAI01.40.25.75.36nolan.tual@inserm.fr
VENISSELaurenceAI01.40.25.75.33laurence.venisse@inserm.fr
YAHIAOUIKatiaDoctorantkatia_yahiaoui@hotmail.fr
ZALGHOUTSaraDoctorantsarazalghout95@gmail.com