Postdoctoral Researcher or Project Researcher in Neurosciences


The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world. The Faculty of Health Sciences… Read more »

Targeting PN-1 to control bleeding in hemophilia


Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia Aymonnier K, Kawecki C, Venisse L, Boulaftali Y, Christophe OD, Lenting PJ, Arocas V, de Raucourt E, Denis CV, Bouton MC 2019 • Blood • [pdf] Hemophilia A and B, diseases caused by the lack of factor VIII (FVIII) and factor IX (FIX) respectively, lead to… Read more »

A postdoc position in U1152 (Bichat Hospital)


A post-doctoral position is available for one year, in the first instance, in Pr. Jean-Michel Sallenave’s laboratory (see address below) in the INSERM Unit 1152 (Physiopathologie et Epidémiologie des maladies respiratoires). Starting date as early as February 2020. The successful candidate will have recently obtained a PhD in Immunology, and will have expertise in FACS technology and cell biology/molecular biology techniques. The project aims at… Read more »

Bronchodilation induced by PGE2 is impaired in Group-III pulmonary hypertension


Bronchodilation induced by PGE2 is impaired in Group-III pulmonary hypertension Ozen G, Benyahia C, Mani S, Boukais K, Silverstein AM, Bayles R, Nelsen AC, Castier Y, Danel C, Mal H, Clapp LH, Longrois D, Norel X 2019 • Br J Pharmacol • [pdf] BACKGROUND AND PURPOSE: In patients with pulmonary hypertension (PH) associated with lung disease and/or hypoxia (Group III), a reduction… Read more »

Société AMBIOTIS recherche un TR supérieur de laboratoire à Toulouse


 La société AMBIOTIS basée à Toulouse est reconnue par la communauté scientifique internationale, pour sa capacité unique à travailler sur la résolution de la réponse inflammatoire de manière innovante. La société travaille avec les industries Pharmaceutiques, Biotechnologiques, Cosmétiques et d’Aliments Santé. Nous vous proposons de travailler dans un environnement innovant, à la pointe de la technologie et en lien avec… Read more »

Tridek-one in the INSERM journal.


In issue 44 of the INSERM journal, an article is devoted to the Tridek-one startup whose 2 scientific co-founders are Giuseppina CALIGIURI and Antonino NICOLETTI who lead Team 1. Read the Article.

Ticagrelor in Patients with Stable Coronary Disease and Diabetes


Ticagrelor in Patients with Stable Coronary Disease and Diabetes Steg PG, Bhatt DL, Simon T, Fox K, Mehta SR, Harrington RA, Held C, Andersson M, Himmelmann A, Ridderstrale W, Leonsson-Zachrisson M, Liu Y, Opolski G, Zateyshchikov D, Ge J, Nicolau JC, Corbalan R, Cornel JH, Widimsky P, Leiter LA, Committee TS, Investigators 2019 • N Engl J Med • [pdf] BACKGROUND:… Read more »

Mitigation of monocyte driven thrombosis on cobalt chrome surfaces by polyurethane coatings


Mitigation of monocyte driven thrombosis on cobalt chrome surfaces in contact with whole blood by thin film polar/hydrophobic/ionic polyurethane coatings Gossart A, Letourneur D, Gand A, Regnault V, Ben Mlouka MA, Cosette P, Pauthe E, Ollivier V, Santerre JP 2019 • Biomaterials • [pdf] Monocytes are active at the crossroads between inflammation and coagulation processes since they can secrete pro-inflammatory cytokines… Read more »

Immunometabolism in CVD


Giuseppina Caligiuri (Team 1) and Danilo Norata (University of Milan) present the content of a Cardiovascular Research spotlight issue focusing on immunometabolism. Link to issue. Aim of this Spotlight Issue is to present an overview of how changes in metabolic pathways of immune cells impact their function in the context of cardiovascular and metabolic diseases. Moreover, classical risk factors affect… Read more »

Mechanotransduction, immunoregulation, and metabolic functions of CD31 in CVD


Mechanotransduction, immunoregulation, and metabolic functions of CD31 in cardiovascular pathophysiology Caligiuri G 2019 • Cardiovasc Res • [pdf] Biomechanical changes in the heart and vessels drive rapid and dynamic regulation of blood flow, a vital process for meeting the changing metabolic needs of the peripheral tissues at any given point in time. The fluid movement of the blood exerts haemodynamic stress… Read more »

ISTH honors Martine Jandrot-Perrus amongst four other members with Esteemed Career Awards


The ISTH honored Martine Jandrot-Perrus (Team 6) amongst four other members with the Esteemed Career Award at the ISTH 2019 Congress Opening Ceremony. These awards are presented annually to individuals whose career contributions have significantly advanced the scientific community’s understanding of diseases and disorders that affect hemostasis. Their accomplishments are internationally regarded as exemplary models of research and mentoring excellence…. Read more »

Safety and Tolerability, PK, and PD of an Antiplatelet GPVI Fab


Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab Voors-Pette C, Lebozec K, Dogterom P, Jullien L, Billiald P, Ferlan P, Renaud L, Favre-Bulle O, Avenard G, Machacek M, Pletan Y, Jandrot-Perrus M 2019 • Arterioscler Thromb Vasc Biol • [pdf]  • [Editorial] Objective– ACT017 is a novel, first in class, therapeutic antibody to platelet GPVI… Read more »

Thierry Lhermitte and FRM representatives at the LVTS

In the context of the FRM grant obtained by Fredéric Chaubet following the tender “Pionnier de la Recherche, Chimie pour la Médecine", Thierry Lhermitte, supporter of the FRM, and several foundation's members visited the laboratory. The project focuses on the tretament of intracranial aneuryms with novel bioactive devices and involves, in addition to the LVTS, two research teams from the... Read more »

Tridek‐One raises € 3 million from Advent France Biotechnology and Advent Life Science

Tridek One, Paris, June 4, 2019 ‐ Tridek One, a biotech company specialized in the development of products for the treatment of immune disorders, is pleased to announce a first round of funding of 3 million euros with leading investors Advent France Biotechnology and Advent Life Sciences. Tridek One was founded in 2018 by Dr. Giuseppina Caligiuri and Professor Antonino Nicoletti, researchers in... Read more »

Functionalized polymer microbubbles to target thrombus


Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus Li B, Aid-Launais R, Labour MN, Zenych A, Juenet M, Choqueux C, Ollivier V, Couture O, Letourneur D, Chauvierre C 2019 • Biomaterials • [pdf] Thrombotic diseases rarely cause symptoms until advanced stage and sudden death. Thus, early detection of thrombus by a widely spread imaging modality… Read more »

Université de Paris : signature scientifique et logos


L’Université de Paris (UP) est née ce qui peut considérablement augmenter notre visibilité internationale. Il convient désormais de pérenniser l’IDEX et sa dotation de plusieurs centaines de millions d’euros dont l’UP ne perçois actuellement que les intérêts au cours de la phase dite probatoire. L’acquisition définitive de l’IDEX dépend de l’évaluation positive par le même jury international qui vient de… Read more »

Relationship of Iron Deposition to Calcium Deposition in Human Aortic Valve Leaflets


Relationship of Iron Deposition to Calcium Deposition in Human Aortic Valve Leaflets Morvan M, Arangalage D, Franck G, Perez F, Cattan-Levy L, Codogno I, Jacob-Lenet MP, Deschildre C, Choqueux C, Even G, Michel JB, Back M, Messika-Zeitoun D, Nicoletti A, Caligiuri G, Laschet J 2019 • J Am Coll Cardiol • [pdf] BACKGROUND: Intraleaflet hematomas are associated with advanced stages of… Read more »

Haemodynamic stress-induced breaches of the arterial intima


Haemodynamic stress-induced breaches of the arterial intima trigger inflammation and drive atherogenesis Franck G, Even G, Gautier A, Salinas M, Loste A, Procopio E, Gaston AT, Morvan M, Dupont S, Deschildre C, Berissi S, Laschet J, Nataf P, Nicoletti A, Michel JB, Caligiuri G 2018 • Eur Heart J • [pdf] Aims: Inflammatory mediators, including blood cells and their products, contribute… Read more »

Catherine Boileau awarded the grand prize of scientific recognition by the Queen of Belgium

Thursday, April 25th 2019: Prof. Catherine Boileau, co-leader of Team 2 and Head of Genetics Department of Bichat Hospital was awarded the grand prize of scientific recognition by the Queen of Belgium. Professor Boileau and her team have made significant and multiple contributions  in understanding the mechanisms responsible for the appearance of aortic aneurysms. With the hope that — as for... Read more »

Prof. PG Steg: appointed “Vice President for Research” of the Executive Board of AP-HP


Prof. Philippe Gabriel Steg (head of Team 5) has been appointed “Vice President for Research” of the Executive Board of the AP-HP on joint proposal of deans, university presidents and Inserm. The Management Board is chaired by the Director General and has two other vice presidents: the president of the medical commission of establishment of the AP-HP, Prof. Christmas Garabedian, is… Read more »

Campagne nationale « doctorat handicap » pour 2019


Le MESRI lance la campagne nationale « doctorat handicap » pour 2019. Voici les information pour l’ED BioSPC: LES DOSSIERS DEVRONT ETRE RETOURNES A L’ED AU PLUS TARD LE MERCREDI 27 MARS 2019. Dossier de candidature en format Word, Pièces annexes réunies en un seul PDF. Pour les équipes Paris Descartes ; Pour les équipes Paris Diderot ; Comme les… Read more »

Webconf du LVTS


Dans la mesure du possible, les séminaires du LVTS du vendredi seront désormais diffusés en direct en webconf. Pour vous connecter: 1/ utiliser GOOGLE CHROME (il est possible que Firefox fonctionne aussi…) 2/ aller à cette adresse : (à partir de 11h55).

Cycle de formation hygiène et sécurité Nouveaux entrants


A noter : les présentations seront faites en français Mardi 29 janvier 2019 (9h00 – 16h45) – Tronc commun obligatoire : organisation de la prévention, conduite à tenir en cas d’accidents, médecine de prévention, prévention du risque électrique, prévention du risque incendie et sûreté et prévention du risque attentat Un formulaire d’inscription format papier est à remplir et faire signer par son… Read more »



EXPERIMENTATION ANIMALE RONGEURS:  LES 3 R – MODULE 1 : REDUCTION Pour répondre aux besoins de formation continue des personnels concernés par l’expérimentation animale, la Délégation Régionale Inserm Paris 5 et l’Université Paris Descartes se sont mobilisées pour organiser dès le début de l’année plusieurs actions permettant aux agents de répondre aux obligations règlementaires. Ces actions sont également proposées aux… Read more »

Anti-PCSK9 and CV outcomes after acute coronary syndrome


Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM, Committees OO, Investigators 2018 • N Engl J… Read more »

Post-doctoral positions in vascular ECM, development and disease


Post-doctoral positions in vascular ECM, development and disease Cleveland Clinic Lerner Research Institute Post-doctoral fellowships are available in Suneel Apte’s laboratory at the Cleveland Clinic Lerner Research Institute (LRI), Cleveland, USA. The project area will be extracellular matrix in vascular development and disease, specifically aortic aneurysm. The positions will suit recent PhDs, MD/PhDs or MDs with an interest in proteases,… Read more »

Inflammation,MMP, and PGE2 in human vascular wall


Inflammation increases MMP levels via PGE2 in human vascular wall and plasma of obese women Ozen G, Boumiza S, Deschildre C, Topal G, Longrois D, Jakobsson PJ, Michel JB, Jacob MP, Chahed K, Norel X 2018 • Int J Obes (Lond) • [pdf] BACKGROUND AND OBJECTIVES: Matrix metalloproteinases (MMPs) are involved in several inflammatory processes including obesity-related vascular diseases and graft… Read more »



Objectif: Mise à jour des connaissances afin de répondre aux exigences réglementaires de formation continue (3 jours de formation obligatoire tous les 6 ans, conformément à la directive 2010/63UE). Public: Personnels INSERM niveau concepteur (ou niveau 1 ou une autorisation d’experimenter valable au 1er février 2013). Modules de formation de 1H à 3H Date limite d’inscription sur sirene fixée au… Read more »

Apprentis chercheurs rentrée 2018


Le temps est à nouveau venu pour participer au programme national ‘Apprentis chercheurs’. Votre mission: accueillir un binôme constitue de un eleve de 3e et un eleve de 1ere au sein de votre laboratoire La fréquence: une demi journée par mois (8 au total) Leur objectif: suivre un projet de recherche sur l’année, qu’ils présenteront en quelques minutes dans le… Read more »

Endothelium, from development to pathology


L’ITMO Physiopathologie Métabolisme Nutrition organise un symposium ayant pour thématique l’Endothelium. Il se tiendra le 4 octobre 2018 à Paris (Amphithéâtre Buffon, 15 rue Hélène Brion, Paris 13). Le programme abordera différents aspects de recherche sur l’endothelium, du développement à la pathologie, et étendue à différents organes. Il inclura une conférence générale donnée par le Professeur Eli Keshet, de l’Université… Read more »

Platelets and vascular integrity


Platelets and vascular integrity: how platelets prevent bleeding in inflammation Ho-Tin-Noe B, Boulaftali Y, Camerer E 2018 • Blood • [pdf] Platelets play a central role in primary hemostasis by forming aggregates that plug holes in injured vessels. Half a century ago, detailed studies of the microvasculature by electron microscopy revealed that under inflammatory conditions that do not induce major disruption… Read more »

Thombus NETs impairs thrombolysis in stroke


Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke Ducroux C, Di Meglio L, Loyau S, Delbosc S, Boisseau W, Deschildre C, Ben Maacha M, Blanc R, Redjem H, Ciccio G, Smajda S, Fahed R, Michel JB, Piotin M, Salomon L, Mazighi M, Ho-Tin-Noe B, Desilles JP 2018 • Stroke • [pdf] BACKGROUND AND PURPOSE: Neutrophil Extracellular Traps… Read more »

Microvascular thombosis is an early response to cerebral arterial occlusion


Downstream Microvascular Thrombosis in Cortical Venules Is an Early Response to Proximal Cerebral Arterial Occlusion Desilles JP, Syvannarath V, Di Meglio L, Ducroux C, Boisseau W, Louedec L, Jandrot-Perrus M, Michel JB, Mazighi M, Ho-Tin-Noe B 2018 • J Am Heart Assoc • [pdf] BACKGROUND: Previous experimental studies have shown that downstream microvascular thromboinflammation is involved in brain damage from acute… Read more »

P8RI dampens IR-induced intestinal injury


Peptide binding to cleaved CD31 dampens ischemia/reperfusion-induced intestinal injury Hoang QT, Nuzzo A, Louedec L, Delbosc S, Andreata F, Khallou-Laschet J, Assadi M, Montravers P, Longrois D, Corcos O, Caligiuri G, Nicoletti A, Michel JB, Tran-Dinh A 2018 • Intensive Care Med Exp • [pdf] BACKGROUND: CD31 is a key transmembrane neutrophil immunoregulatory receptor. Mesenteric ischemia/reperfusion-induced neutrophil activation leads to a… Read more »

Poll to choose the conference/seminar day


Some members have requested to change the day (currently the Fridays) of the weekly conference/seminar of the LVTS for next year (from Sept 2018 onward). The Conseil de Laboratoire (13th July 2018) has decided that all LVTS members should vote to choose the conference/seminar. You have until the 31st of August to vote (upper part of the sidebar of our… Read more »

Macrophage CD31 Signaling in Dissecting Aortic Aneurysm


Macrophage CD31 Signaling in Dissecting Aortic Aneurysm Andreata F, Syvannarath V, Clement M, Delbosc S, Guedj K, Fornasa G, Khallou-Laschet J, Morvan M, Even G, Procopio E, Gaston AT, Le Borgne M, Deschamps, L, Nicoletti A, Caligiuri G 2018 • JACC • [pdf] + Editorial from P Libby: Biologically-Based Therapies for Aortic Diseases • Link Background The authors recently found that a CD31… Read more »

Nanoparticles of Metal-Organic Frameworks


Nanoparticles of Metal-Organic Frameworks: On the Road to In Vivo Efficacy in Biomedicine Simon-Yarza T, Mielcarek A, Couvreur P, Serre C 2018 • Adv Mater. • [pdf] In the past few years, numerous studies have demonstrated the great potential of nano particles of metal-organic frameworks (nanoMOFs) at the preclinical level for biomedical applications. Many of them were reported very recently based… Read more »

Abiotic sequence-coded oligomers as taggants


Abiotic sequence-coded oligomers as efficient in vivo taggants for identification of implanted materials Karamessini D, Simon-Yarza T, Poyer S, Konishcheva E, Charles L, Letourneur D, Lutz JF. 2018 • Angew Chem Int Ed Engl • [pdf] Sequence-defined oligourethanes were tested as in vivo taggants for implants identification. The oligomers were prepared via an orthogonal solid-phase iterative approach and thus contained a… Read more »

Catherine Boileau awarded the “Grand Prix Lefoulon-Delalande 2018”


Catherine BOILEAU (Team 2) was awarded, together with Helen Hobbs (University of Texas Southwestern Medical School, Dallas – Etats-Unis) and Nabil Seidah (Institut de recherches cliniques de Montréal – Canada), the Grand Prix de la Fondation Lefoulon Delalande during a ceremony held on Wednesday, May 30 2018 under the Dome of the Institut de France. The ceremony was chaired by Mr…. Read more »

Journée microscopie Univ. Paris Diderot – le 31 mai 2018


Le 31 mai, une demi-journée dédiée à la microscopie photonique est organisée à Paris Diderot. Une journée avec des présentations de plateformes, des presentations scientifiques mais aussi avec de tables rondes, afin de créer un réseau de competences. A l’amphi Turing. Inscription libre, mais obligatoire: Journée microscopie Paris Diderot

Prix de thèse de la Chancellerie des Universités de Paris


La chancellerie vient de lancer son Appel à candidature pour les prix solennels 2018  qui récompense l’excellence de 50 thèses ( soutenues en 2017) dans les différents domaines LSH, Médecine ,Sciences… Lire  le document (à télécharger ici)  pour  la constitution du dossier de candidature ( nouvelle procédure cette année). Les candidatures sont transmises à la chancellerie par l’université, aucune candidature… Read more »

MOOC: Tissue and Organ Bioengineering


Marie-Noëlle Labour (Team 3) is actively involved in the MOOC “Tissue and Organ Bioengineering”. You can freely attend and register to this MOOC until 8th June 2018. It will be broadcasted between the 14 May and 17 June 2018. Link to subscribe

Campagne d’appréciation ITA 2018


Début de la campagne : 27 février 2018 La campagne d’appréciation des personnels ingénieurs, techniciens et administratifs de l’Inserm débute ce mardi dans Gaia. Vous êtes invités à préparer vos entretiens annuels d’appréciation dès à présent. Validation des dossiers jusqu’au : 3 avril 2018 En savoir plus…

Ethique et intégrité scientifiques

Il y a plusieurs mois de cela, Pierre Corvol remettait un rapport portant sur le "Bilan et des proposition de mise en oeuvre de la charte nationale d'intégrité scientifique" à Thierry Mandon, alors secrétaire d'Etat chargé de l'Enseignement Supérieur et de la Recherche. Ce rapport débute ainsi: La recherche est un superbe métier, pratiqué avec rigueur et honnêteté par l’immense... Read more »

Improved prognosis in NSTEMI patients


A recent publication from Team 5 has been released in Circulation demonstrates that patients with high risk non–ST-segment–elevation myocardial infarction (NSTEMI) that undergo coronary angiography within the initial 12 hours after admission had a lower risk of ischemic outcomes at 180 days. Timing of Angiography and Outcomes in High-Risk Patients With Non–ST-Segment– Elevation Myocardial Infarction Managed Invasively Insights From the TAO Trial (Treatment… Read more »

External applicability of the COMPASS trial


External applicability of the COMPASS trial: an analysis of the reduction of atherothrombosis for continued health (REACH) registry Darmon A, Bhatt DL, Elbez Y, Aboyans V, Anand S, Bosch J, Branch KR, Connolly SJ, Dyal L, Eikelboom JW, Fox KAA, Keltai K, Probstfield J, Yusuf S, Abtan J, Sorbets E, Eagle KA, Ducrocq G, Steg PG 2017 • Eur Heart… Read more »

Systemic Atherosclerosis and Stroke Etiologies


Prevalence of Systemic Atherosclerosis Burdens and Overlapping Stroke Etiologies and Their Associations With Long-term Vascular Prognosis in Stroke With Intracranial Atherosclerotic Disease Hoshino T, Sissani L, Labreuche J, Ducrocq G, Lavallee PC, Meseguer E, Guidoux C, Cabrejo L, Hobeanu C, Gongora-Rivera F, Touboul PJ, Steg PG, Amarenco P, Investigators A 2017 • JAMA Neurol • [pdf] Importance: Patients who have experienced… Read more »

Dominique Le Guludec appointed head of the Haute Autorité de Santé


Dominique Le Guludec, Professor of Biophysics and Nuclear Medicine at the UFR of Medicine at Paris Diderot University, Director of the Department of Nuclear Medicine and Biophysics at Bichat Hospital – Claude Bernard, APHP and Head of the Imaging Team Cardiovascular in the Translational Vascular Research Laboratory, has just been appointed head of the Haute Autorité de Santé (HAS). Dominique… Read more »

Radical Copolymerization of Vinyl Ethers and Cyclic Ketene Acetals as a Versatile Platform to Design Functional Polyesters


Radical Copolymerization of Vinyl Ethers and Cyclic Ketene Acetals as a Versatile Platform to Design Functional Polyesters Tardy A, Honore JC, Tran J, Siri D, Delplace V, Bataille I, Letourneur D, Perrier J, Nicoletti C, Maresca M, Lefay C, Gigmes D, Nicolas J, Guillaneuf Y 2017 • Angew Chem Int Ed Engl • [pdf] For the first time, the free-radical copolymerization… Read more »

ACTICOR biotech first-in-human clinical trial in healthy volunteers


Acticor Biotech, a clinical stage biotechnology company (raised on the basis of a work initiated in Team 6 of U1148) involved in the acute phase of thrombotic diseases, including stroke and myocardial infarction, today announced the agreement of Dutch Authorities for the initiation of a phase I clinical trial in healthy volunteers with its drug candidate, ACT017. ACT017 is a… Read more »

Post-doctoral position in UMR Inserm 1011 – Institut Pasteur de Lille – University of Lille (headed Bart Staels)


A post-doctoral position is available in the « nuclear receptors, cardiovascular diseases and diabetes” laboratory, team 1 (Nuclear receptor and metabolic disease). The successful applicant will be involved in the development of metabolic disorders in mouse models (obesity, insulin-resistance, T2D, NASH/NAFLD…). That will include the characterization of the metabolic phenotype, the determination of the underlying molecular mechanisms, as well as the… Read more »

Un nouvel outil web à Paris Diderot pour chercher des financements


Après une phase test lancée en 2016 par la Direction d’aide à la recherche et à l’innovation (DARI), en lien avec USPC, l’université P7 s’est récemment dotée d’un moteur de veille web sur les appels à projets de recherche, RESEARCHconnect. Cet outil permet d’élargir le spectre des fonds auxquels vous pourrez candidater, tout en retrouvant de manière centralisée les fonds… Read more »

Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI2


Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI2 : a safer alternative to COX-2 inhibition Ozen G, Gomez I, Daci A, Deschildre C, Boubaya L, Teskin O, Uydes-Dogan BS, Jakobsson PJ, Longrois D, Topal G, Norel X 2017 • Br J Pharmacol • [pdf] BACKGROUND AND PURPOSE: The side effects of cyclooxygenase-2 (COX-2) inhibitors on the cardiovascular… Read more »

Offre de thèse à Bordeaux


Veuillez trouver ci-joint une offre d’allocation doctorale, à diffuser aux étudiants en Master ou ayant déjà obtenu un Master, afin de réaliser une thèse dans l’équipe UMR-Inserm U1034 à Bordeaux. PhD fellowship_Inserm U1034

TF1 talks about Fucoidans


Cedric Chauvierre (Team 3) has given an interview on the use of fucoidans to trace early atherothrombotic lesions for the TV news on the first French channel (TF1) on the 14th August 2017. You can see it here: LINK.

Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice


Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice – Implications for Superficial Erosion Franck G, Mawson T, Sausen G, Salinas M, Santos Masson G, Cole AP, Beltrami Moreira M, Chatzizisis Y, Quillard T, Tesmenitsky Y, Shvartz E, Sukhova GK, Swirski FK, Nahrendorf M, Aikawa E, Croce K, Libby P 2017 • Circ Res • [pdf] Rationale:… Read more »

Free DNA precipitates calcium phosphate apatite crystals in the arterial wall in vivo


Free DNA precipitates calcium phosphate apatite crystals in the arterial wall in vivo Coscas R, Bensussan M, Jacob MP, Louedec L, Massy Z, Sadoine J, Daudon M, Chaussain C, Bazin D, Michel JB 2017 • Atherosclerosis • [pdf] BACKGROUND AND AIMS: The arterial wall calcium score and circulating free DNA levels are now used in clinical practice as biomarkers of cardiovascular… Read more »

D Letourneur granted the 2017 Asian Polymer Association (APA)’s Jubilee Award


Didier Letourneur (Director of LVTS, head of Team 3) has been awarded the 2017 Asian Polymer Association (APA)’s Jubilee Award. APA was founded in 2007 at the premises of Indian Institute of Technology, New Delhi, India, The society involves academicians, scientists and technologists from all over the Asian countries providing a well knitted structure of the society. Vision of… Read more »

Prix de thèse de la Chancellerie


La Chancellerie des Universités de Paris vient de lancer son appel à candidatures pour la campagne 2017 des Prix Solennels de La Chancellerie. Les dossiers de candidatures seront étudiés par la Commission d’évaluation  de l’université  le lundi 15 mai 2017. La date limite de dépôt des dossiers à la DARI a été fixée au 12 mai  2017. (Mme Meneceur, Bureau… Read more »

Prof G Jondeau, coordinator of VASCERN


Prof Guillaume JONDEAU (Team 2) is the corrdinator of VASCERN, the European Reference Network on Rare Multisystemic Vascular Diseases. “The VASCERN project aims to facilitate and improve diagnosis, treatment and care for ALL patients suffering from Rare Multisystemic Vascular Diseases, thus enhancing access to care, and improving quantity and quality of life of these patients. Networking, sharing and spreading our expertise,… Read more »

Signature of the SAVE-BRAIN and SURVI MSD-Avenir projects


On the 18th April 2017, D Blazy (Président du Conseil Scientifique de MSD-Avenir) on the behalf of C Schiever (Président du CA de MSD-Avenir), M Hirsch (Directeur Général de l’AP-HP), the Prof Y Levy (Président Directeur Général de l’INSERM), in the presence of the Prof P Ruszniewski (Doyen de l’UFR de médecine de l’Université Denis Diderot) and of F Crémieux (Directeur… Read more »

The lung, a major site of platelet biogenesis!!


A report published in Nature demonstrate that up to 50% of the platelet production derives form megacaryocytes circulating through the lungs! The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors Emma Lefrançais, Guadalupe Ortiz-Muñoz, Axelle Caudrillier, Beñat Mallavia, Fengchun Liu, David M. Sayah, Emily E. Thornton, Mark B. Headley, Tovo David, Shaun R. Coughlin, Matthew… Read more »

Appel à candidature 2017 pour Prix de thèse du GERLI en lipidomique


Le Groupe d’Etude et de Recherche en Lipidomique fait appel à candidatures pour son prix de thèse. Ce prix récompense un travail dans le domaine des lipides, réalisé dans un laboratoire français ; la thèse aura été soutenue en 2016. Le montant du prix est de 1500€. Le prix de thèse décerné par le conseil scientifique du GERLI sera remis… Read more »

Free DNA precipitates calcium phosphate apatite crystals in the arterial wall in vivo


Free DNA precipitates calcium phosphate apatite crystals in the arterial wall in vivo Coscas R, Bensussan M, Jacob MP, Louedec L, Massy Z, Sadoine J, Daudon M, Chaussain C, Bazin D, Michel JB 2017 • Atherosclerosis • [pdf] BACKGROUND AND AIMS: The arterial wall calcium score and circulating free DNA levels are now used in clinical practice as biomarkers of cardiovascular… Read more »

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke


Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials Costa F, van Klaveren D, James S, Heg D, Raber L, Feres F, Pilgrim T, Hong MK, Kim HS, Colombo A, Steg PG, Zanchin T, Palmerini T, Wallentin L, Bhatt DL,… Read more »

Plusieurs propositions de postdoc pour les US


Cellular Mechanobiology Lab at the University at Buffalo Postdoctoral candidate Téléchargez l’annonce…   Research Positions Cardiac Physiology Postdoctoral Fellow/Instructor Téléchargez l’annonce… An NIH-sponsored postdoctoral fellowship  Available on human genome editing for blood disease modeling and treatment Téléchargez l’annonce…   Postdoctoral Fellow Harvard Medical School, Beth Israel Deaconess Medical Center (BIDMC) Téléchargez l’annonce…

Guide pour ‘Pratiquer une recherche intègre et responsable’


Ce guide est destiné à tous les acteurs de la recherche, quels que soient leur appartenance disciplinaire, leur niveau de responsabilité et leur statut. Il vise aussi à répondre aux questions que peuvent se poser les étudiants de master et doctorants sur de nombreux aspects de leur activité et à leur donner quelques pistes pour la pratiquer de manière responsable…. Read more »

Postdoctoral Research Fellow position in Nantes


Postdoctoral Research Fellow position available at INSERM UMR1064 Center for Research in Transplantation and Immunology, France Title: Antigen-specific Tregs in transplantation The laboratory: The Center for Research in Transplantation and Immunology (CRTI) is a research unit (UMR 1064) dedicated to transplantation science and immunology since 1993 in Nantes. The CRTI (3,000 m2 of laboratory surface area and two animal facilities) currently… Read more »

3 appels à projets USPC en cours


Trois appels à projets ont été publiés pour 2017 dans le cadre des bureaux de USPC à l’international: AAP USPC-NUS (Singapour), La date limite de candidature est le 30 janvier 2017. Le contact est : AAP USPC-CIN(Argentine) ; La date limite de candidature est le 15/02/2017. Le contact est AAP USPC-USP (Brésil) : La date limite de candidature est le 1er mars 2017 ; le… Read more »

Assistant/Associate Professor – Vascular Biology in Geneva


Posted on 19 Dec 2016 University of Geneva · The Faculty of Medicine Switzerland, Genève Job description The Faculty of Medicine of the University of Geneva is seeking to fill a position of: Assistant or Associate Professor in vascular biology in the context of inflammation and immunology. Charge: This full-time position will involve undergraduate and postgraduate teaching in vascular biology and immunology , as… Read more »

Concours chercheurs session 2017


Le service RH de l’INSERM nous informe de l’ouverture de la campagne des concours chercheurs session 2017 (CR et DR). Vous trouverez ci-joint la lettre d’information relative à cette campagne, le tableau de répartition des postes ainsi que l’affiche de communication. Modalités de candidature : Concours CR : Date limite de Dépôt des dossiers (CR1 & CR2) : le 12 Janvier 2017 –… Read more »

Fiches produits chimiques


Le Bureau de coordination de la prévention de l’Inserm (BCPR) a élaboré en collaboration avec le Service prévention des risques de l’Institut Pasteur des fiches synthétiques destinées à tous ceux qui manipulent des produits chimiques dangereux. Elles permettront d’identifier rapidement les risques et de manipuler les produits en toute sécurité. Télécharger les version électroniques des fiches

FRM : appel à projets


La Fondation pour la recherche médicale finance des projets dans le cadre de son programme “Espoir de la recherche : amorçage de jeunes équipes”. Montant : 2 000 000 € Date limite de candidature : 24 octobre 2016 Lien vers le site

Lancement du programme d’accueil d’étudiants Chinois


L’Université Sorbonne Paris Cité (UPSC) a signé en juin 2014 un accord avec le China Scholarship Council1 (CSC), un organisme gouvernemental chinois, pour permettre l’accueil dans les établissements et les ED de USPC de doctorants chinois. La procédure est lancée, attention, les délais sont courts!! Procedure csc_modele-sujet_2016-2017

Calendrier: qualification des enseignants-chercheurs 2017


Ouverture du serveur Antares : jeudi 08 septembre 2016, 10h (heure de Paris) Clôture des inscriptions : Mardi 25 octobre 2016, 16h (heure de Paris) Mise en ligne des rapporteurs sur GALAXIE : à partir du vendredi 25 novembre 2016 Date à laquelle la thèse ou l’habilitation doit avoir été soutenue : mercredi 14 décembre 2016 inclus Date limite d’envoi… Read more »

RHU call results: LVTS involved in 5 granted projects!


The ‘RHU‘ (Recherche Hospital Universitaire) action is to support translational research projects in health or clinical research, which are to be based on fundamental research in biology, epidemiology, social science or health economics and extend for a benefit for the care of patients, improving the understanding of diseases, more effective and better tolerated treatments, or a performance improvement of care systems. The… Read more »

3 postes INSERM ouverts à la mobilité interne vers le LVTS


3 postes INSERM sont ouverts à la mobilité au sein de notre unité INSERM U1148 LVTS: • Un poste d‘ingénieur(e) d’étude en expérimentation et instrumentation biologiques —> Voir le profil du poste • Un poste d’Animalier  —> Voir le profil du poste • Un poste de Technicien biologiste —> Voir le profil du poste Pour toute information, veuillez contacter notre secrétariat ou la DR Paris 7.

[Update] My thesis in 180s


We are proud that one of our PhD student, Charlotte Rasser (Team 1), is one of the final candidates of the “My thesis in 180 sec” contest. Link. Update: Charlotte was amongst the very finalists (16 students selected out of 560 candidates from all over France) of the contest which was organized in Bordeaux on the 31st May 2016

The PCSK9 story


A paper in the Eur Heart Journal from Nail Seidah that recapitulates the discovery of the PCSK9 mutations in familial hypercholesterolemia made by Marianne Abifadel and Catherine Boileau (Team 2) in 2003. Read the paper..

Early detection of strokes


Télématin broadcasted on the 13rd May 2016 an interview from Prof Pierre Amarenco (Team 5) where it is explained why we should detect stroke as soon as possible. This is related to a paper published this year by P Amarenco et al (N Engl J Med 2016. 374:1533) describing the results obtained from the ‘’ project that was designed to establish the contemporary profile, etiologic… Read more »