IdeX Suite à la visite sur site du jury international en septembre 2021, et l’audition du 20 janvier dernier de la délégation de l’université et de ses partenaires de l’Inserm et du CNRS, le Premier ministre a annoncé la labellisation définitive d’Université Paris Cité au titre des Initiatives d’Excellence. Lire la suite > Nouveaux nom et logos Université Paris Cité,… Read more »
Results from this trial will be presented in a webinar on Wednesday 23 February at 11.00am CET Sign-up link Key points from this study:• Achievement of the study’s primary endpoint, confirming glenzocimab’svery favorable safety profile• Reduction in the number of intracerebral hemorrhages and mortalityamong patients treated with glenzocimab Read the Press Release
Mieux connaitre le modèle sourispour optimiser vos résultats d’expérience
The PUMS College YouTube channel, directed by Boris Hansel (Team 3), is a large audience channel. PuMS (Pour une Meilleure Santé) is a health channel concept run by a college of doctors whose objective is to provide 100% reliable information and practical advice on a daily basis. At the origin of PuMS… PuMS was founded in 2019 by Pr Boris… Read more »
Ce semestre, la direction des bibliothèques (DGDBM) propose des formations à la Science ouverte pour les enseignants-chercheurs, chercheurs, personnels BIATSS impliqués dans la recherche et doctorants. En voici le détail ci-dessous. Accompagnement à la recherche pour les enseignants-chercheurs, chercheurs et personnels BIATSS : Déposer dans l’archive ouverte HAL : 16 février, 16 mars, 13 avril ou 11 mai 2022 – en ligne… Read more »
Read the January 2022 issue of the Magazine de l’INSERM. Giuseppina Caligiuri’s (Team 1) work on the CD31 is highlighted. Read the Jan 2022 issue
Location: Université Sorbonne Paris Nord – Bobigny (France) Start date: From 14 March 2022 (negotiable) Contract duration: 24-month fixed-term contract (renewable) Reporting line: Raphaël Lévy (raphael.levy@univ-paris13.fr) We are recruiting two postdoctoral researchers to work on the first replication project in nanobiotechnology. The successful applicants will join NanoBubbles. NanoBubbles is a European Research Council (ERC) Synergy project that aims at better understanding… Read more »
Offre de post doc dans le laboratoire de Nicolas Venteclef. Postdoc position Venteclef Lab Paris
La DGESIP a diffusé une nouvelle circulaire concernant l’accueil des publics internationaux (étudiants, doctorants, chercheurs et personnels) en mobilité entrante pour le semestre 2. Correspondant aux dernières annonces gouvernementales, de nouvelles règles s’appliquent pour notre public international : Pour toute mobilité étudiante “entrante” en période de covid : test PCR ou antigénique négatif. Exception si le schéma vaccinal est complet ET… Read more »
When a blood vessel is blocked by a clot, there is currently only one possible treatment: injecting a substance called Alteplase which dissolves the mass of coagulated blood. However, even if this medicine is quickly broken down by the body, it can cause bleeding and permanently disrupt blood circulation. However, Alina Zenych, within the team of Cédric Chauvierre at the… Read more »
Giuseppina Caligiuri, head of Team 1, was awarded the 2021 Jean-Paul Binet prize (Link). The award ceremony was held on November 24, 2021 and was accompanied by a digital event, broadcast live on November 24, 2021, around 4 successive round tables on the following themes: • The journey of a researcher – from young researcher to research manager • From… Read more »
Prix de Thèse GREMI – Michel Chignard Le GREMI récompense l’auteur d’une thèse concernant l’inflammation, soutenue dans une université française en 2021. Montant : 1 600 €. Date limite de candidature : 31 décembre 2021. Plus d’informations
Acticor Biotech winner of the Prix Galien Medstartup in the category “BEST COLLABORATION IN THE PHARMACEUTICAL OR BIOTECHNOLOGICAL INDUSTRY”,organized by the prestigious Galien Foundation and by Business France. Read the press release Acticor Biotech announces FDA acceptance of its IND Application for Glenzocimab in Acute Ischemic Stroke Read the press release
A 2-year postdoctoral position is available in the Basophils, Mast cells and Immunopathology (BMI) team of the Centre for Research on Inflammation (CRI, INSERM U1149 CNRS ERL8252 University of Paris, Laboratoire d’Excellence INFLAMEX) at the Bichat Medical School, University of Paris, in Paris, France. The expected starting date is January, 1st 2022. Read the full description of the proposal.
miRNA Delivery by Nanosystems: State of the Art and Perspectives Moraes FC, Pichon C, Letourneur D, Chaubet F 2021 •Pharmaceutics • [pdf] MicroRNAs (miRNAs) are short (~21–23 nucleotides), non-coding endogenous RNA molecules that modulate gene expression at the post-transcriptional level via the endogenous RNA interference machinery of the cell. They have emerged as potential biopharmaceuticals candidates for the treatment of various… Read more »
L’institut des Sciences Cardiovasculaires — auquel le LVTS participe — s’associe à l’organisation de la conférence Biomarker of the Future 2021. Deux prix Jeunes chercheurs seront également attribués. Le site web de la conférence (pour info & inscriptions) : www.biomarkersofthefuture.com Ou plus d’informations sur le site de l’institut : https://www.institutcardiovasculaireparis.fr/ BMF 21 Program
GREMI Webinar: Inflammation: you get on my nerves November 5th, 2021 – Free registration on the GREMI website Programme : Lecture 1: Nathalie Kubis “Stroke: a chronic inflammatory disease” – INSERM U1148 Paris. Lecture 2: Claudia Verderio “Microglial microvesicles in motion at the neuron surface: implications in synaptic dysfunction in Alzheimer’s disease” – CNR Milano Italy. Lecture 3: Guy Simonnet… Read more »
If you don’t know the YouTube channel of Dr IZA, this is the perfect occasion to discover it: a new great video has just been published by Ilyass Zouhry (alias Dr IZA): Ilyass is a young and talented pathologist . He is currently a PhD fellow in our research unit (Team 1). You can also follow him on his… Read more »
The winner of this prize is chosen by the donors of the Fondation de l’Avenir from among six high-quality projects. The team of Professor Mikael MAZIGHI (Team 6), neurologist, Adolphe de Rothschild Foundation Hospital in Paris, was chosen for its work on how to advance the treatment of stroke. This Trophy was presented by Serge BRICHET, President Mutualité function publique… Read more »
In vitro strategies to vascularize 3D physiologically relevant models Dellaquila A, Le Bao C, Letourneur D, Simon-Yarza T 2021 •Adv Sci (Weigh) • [pdf] Vascularization of 3D models represents a major challenge of tissue engineering and a key prerequisite for their clinical and industrial application. The use of prevascularized models built from dedicated materials could solve some of the actual limitations,… Read more »
If you would like to scan the last 30 years on the progresses made in understanding innate and adaptive immunity in cardiovascular disease, you can take this course given by Giuseppina Caligiuri (Team 1) at ESC Summer Courses ( 2019). To watch this lecture: https://youtu.be/M204IsFDM-0
Paris, July 1st, 2021 – Acticor Biotech, a clinical stage biotechnology company involved in the acute phase of thrombotic diseases, today announces the end of recruitment in ACTIMIS, its phase 1b/2a study with glenzocimab (ACT017), a novel humanized monoclonal antibody fragment for use in patients with acute ischemic stroke. This therapeutic strategy emerges from the work of Dr Martine Jandrot-Perrus… Read more »
Le Prix CASDEN a été remis au docteur Ludivine ELIAHOU pour son étude clinique sur les effets bénéfiques d’un entraînement combinant endurance et résistance pour des patients atteints du syndrome de Marfan. La remise de ce prix 2020 s’est déroulée hier en visioconférence en présence de Vincent-Nicolas DELPECH, directeur du GHU AP-HP Nord – Université de Paris, de Claude JECHOUX, président CASDEN Banque Populaire, de Marion LELOUVIER, présidente du directoire de la… Read more »
La Commission Européenne vient de publier l’appel à projets « Postdoctoral Fellowships 2021 ». Cet appel reprend les modalités de dépôt des appels à projets « MSCA Individual Fellowship » d’Horizon 2020 qui permet à un post-doctorant d’être financé pour une durée de 2 ou 3 ans. Les départements d’Ingénierie et Management de projet de la DRIVE ont ainsi décidé… Read more »
Si vous souhaitez récupérer les diapos de la présentation faite par Tony le 28 mai 2021 sur le futur Centre de Recherche de l’Hôpital Nord, elles sont disponibles dans l’Intranet–>General Interest Docs.
Le service Eduroam offre un accès sans fil sécurisé à Internet aux personnels des établissements d’enseignement supérieur et de recherche, dans l’enceinte de leur établissement mais également lors de leurs déplacements. Il est maintenant possible d’accéder à ce réseau sur tous les sites et campus d’Université de Paris. Pour utiliser le Wi-Fi d’Université de Paris, vous devez télécharger l’installateur EDUROAM… Read more »
Prof. Marianne Abi Fadel, Dean of the Faculty of Pharmacy at USJ and member of the UMRS1148 Team 2, received the Christophe Mérieux 2021 Prize from the Fondation Christophe et Rodolphe Mérieux- Institut de France. This prize, which will be awarded on June 2, 2021 to the Institut de France, will be mainly dedicated to research projects and humanitarian projects… Read more »
Un poste d’ATER est ouvert dans l’équipe 1 du LVTS. Poste et mission Recherche : Le projet de recherche porte sur la compréhension de l’effet de la température sur la réponse des lymphocytes B dans des modèles expérimentaux chez la souris. Enseignement : Le candidat interviendra principalement au niveau de TP et TD d’immunologie, dans le L2 Sciences du Vivant, la L3 Pro Bio… Read more »
Ambiotis, une société de services de recherche qui travaille avec les industries pharmaceutiques/biotechnologiques, cosmétiques et alimentaires, recherche un chercheur en immuno-inflammation et modèles animaux. Lire l’annonce
L’OPECST a mis en ligne ce jour un rapport sur l’intégrité scientifique de 134 pages. Ci-jointe, la synthèse de 4 pages avec les 10 recommandations: 2021_Synthèse Intégrité scientifique_FR
Coronary stent CD31-mimetic coating favours endothelialization and reduces local inflammation and neointimal development in vivo Diaz-Rodriguez S, Rasser C, Mesnier J, Chevallier P, Gallet R, Choqueux C, Even G, Sayah N, Chaubet F, Nicoletti A, Ghaleh B, Feldman LJ, Mantovani D, Caligiuri G 2021 • Eur Heart J• [pdf] AIMS: The rapid endothelialization of bare metal stents (BMS) is counterbalanced… Read more »
CD31 Mimetic Coating Enhances Flow Diverting Stent Integration into the Arterial Wall Promoting Aneurysm Healing †Cortese J, †Rasser C, Even G, Bardet SM, Choqueux C, Mesnier J, Perrin ML, Janot K, Caroff J, Nicoletti A, Michel JB, Spelle L, §Caligiuri G, §Rouchaud A 2021 • Stroke • [pdf] BACKGROUND AND PURPOSE: Beyond aneurysmal occlusion, metallic flow diverters (FDs) can induce an… Read more »
Le sénat académique d’Université de Paris a validé en décembre dernier un accord avec le China Scolarship Council (CSC) qui prend la suite de l’accord qui avait cours entre USPC et le CSC. Cet accord permet en premier lieu de proposer des sujets de thèses à des étudiants chinois (appel en cours porté par les Écoles Doctorales, cf document joint)…. Read more »
We are proud to announce that Anne Pellé (Team 3) has been promoted and appointed in the “ordre national de la légion d’honneur au grade de chevalier”. Congratulation to her!!
– Approval of phase 2 GARDEN study in France and Brazil – GARDEN will enroll 60 patients hospitalized for COVID19 – First Patient included at University Hospital of Strasbourg Acticor Biotech is a clinical stage biotechnology spin-off of INSERM (built upon the expertise and the results of research conducted by the founders: Dr. Martine Jandrot-Perrus from U1148 Team 6 and Pr…. Read more »
Chicken egg white: Hatching of a new old biomaterial Jalili-Firoozinezhad S, Filippi M, Mohabatpour F, Letourneur D, Scherberich A 2020 • Materials Today • [pdf] Chicken egg white is an abundant, inexpensive and natural source of important proteins such as ovalbumin and lysozyme. Thanks to its bioactivity, easy handling, anti-bacterial activity and biodegradability, egg white is being used since centuries… Read more »
Each year,the Fondation Bettencourt awards prizes for Postdoc training to young investigators. Among the 14 laureates of the 2020 edition, Karen Aymonnier (ex-Team 6 PhD student) received one of the prizes for a project that will be conducted in the Denisa Wagner lab. She will continue to work on the interaction of neutrophils and platelets during thrombosis.
On nous signale qu’il est désormais possible de se connecter à Eduroam en WIFI en utilisant 3 types d’identifiants : – Compte informatique ex Descartes – Compte informatique ex Diderot – Compte informatique UP Liens utiles: https://www.eduroam.fr/ https://u-paris.fr/wi-fi-universite-de-paris-avec-eduroam/
Membranes for Guided Bone Regeneration: A Road from Bench to Bedside Aprile P, Letourneur D, Simon-Yarza T 2020 • Adv Healthc Mater• [pdf] Bone resorption can negatively influence the osseointegration of dental implants. Barrier membranes for guided bone regeneration (GBR) are used to exclude nonosteogenic tissues from influencing the bone healing process. In addition to the existing barrier membranes available… Read more »
Enabling MedTech Translation in Academia: Redefining Value Proposition with Updated Regulations Letourneur D, Joyce K, Chauvierre C, Bayon Y, Pandit A 2020 • Adv Healthc Mater• [pdf] Academic institutions are becoming more focused on translating new technologies for clinical applications. A transition from “bench to bedside” is often described to take basic research concepts and methods to develop a therapeutic… Read more »
The Laboratory for Vascular Translational Science in Paris offers a position of Research Associate (Ingénieur d’Études) in the Team Cardiovascular Bioengineering (head of the team: Didier Letourneur). Read the offer here…
Ci-joint une annonce concernant 2 postes ouverts dans l’équipe ‘‘Immunité Innée et défenses pulmonaires anti-infectieuses” dirigée par le Prof Jean-Michel Sallenave dans l’UMR1152 Inserm ‘Physiopathologie et Epidémiologie des Maladies Respiratoires’. Postdoctoral and technician positions JM Sallenave Carb-X Septembre 2020
Nanomedicine progress in thrombolytic therapy Zenych A, Fournier L, Chauvierre C 2020 • Biomaterials • [pdf] Thrombotic occlusions of blood vessels are responsible for life-threatening cardiovascular disorders such as myocardial infarction, ischemic stroke, and venous thromboembolism. Current thrombolytic therapy, the injection of Plasminogen Activators (PA), is yet limited by a narrow therapeutic window, rapid drug elimination, and risks of hemorrhagic complications…. Read more »
International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH 2020 •… Read more »
FSD_missions en France et à l’étranger_21sept2020_VF
Our research unit is spotlighted in the last issue of the European Heart Journal. Read the full paper: pdf
Phylogenic determinants of cardiovascular frailty, focus on hemodynamics and arterial smooth muscle cells Michel JB 2020 • Physiol Rev • [pdf] The evolution of the circulatory system from invertebrates to mammals has involved the passage from an open system to a closed in-parallel system via a closed in-series system, accompanying the increasing complexity and efficiency of life’s biological functions. The archaic… Read more »
Nouveau fichier de licence pour l’antivirus Kaspersky à retrouver dans ‘Private Links’.
CD31 as a Therapeutic Target in Atherosclerosis Caligiuri G 2020 • Circulation Res • [pdf] The potential of CD31 as a therapeutic target in atherosclerosis has been considered ever since its cloning in the 1990s, but the exact role played by this molecule in the biologic events underlying atherosclerosis has remained controversial, resulting in the stalling of any therapeutic perspective. Due… Read more »
As part of its policy of supporting medical research, the City of Paris annually awards two Grand Prizes to eminent personalities from the Parisian scientific community. Meeting on January 28, 2020, the jury for the Grands Prix de Médecine chose its winners: Philippe-Gabriel Steg (Team 5) and Nicolas Manel. The Grand Prix of Medicine and Medical Research of the City… Read more »
C’est une étape importante pour la réalisation du volet universitaire du Campus hospitalo universitaire Grand Paris Nord qui vient d’être franchie. En effet, après une présentation de l’opération le 17 décembre dernier lors de la Conférence Nationale de l’Immobilier Public (CNIP) le projet a obtenu la labellisation de la Direction de l’Immobilier de l’État (DIE ) qui a émis un… Read more »
Cleaved CD31 as a target for in vivo molecular imaging of inflammation Vigne J, Bay S, Aid-Launais R, Pariscoat G, Rucher G, Sénémaud J, Truffier A, Anizan N, Even G, Ganneau C, Andreata F, Le Borgne M, Nicoletti A, Le Guludec D, Caligiuri G & Rouzet F 2019 • Scientific Reports • [pdf] There is a need for new targets to… Read more »
Le GREMI récompense l’auteur d’une thèse concernant l’inflammation, soutenue dans une université française en 2019. Montant : 1 600 €. Date limite de candidature : 31 décembre 2019. Plus d’informations
The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world. The Faculty of Health Sciences… Read more »
A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke Amarenco P, Kim JS, Labreuche J, Charles H, Abtan J, Bejot Y, Cabrejo L, Cha JK, Ducrocq G, Giroud M, Guidoux C, Hobeanu C, Kim YJ, Lapergue B, Lavallee PC, Lee BC, Lee KB, Leys D, Mahagne MH, Meseguer E, Nighoghossian N, Pico F, Samson Y, Sibon I, Steg PG,… Read more »
Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia Aymonnier K, Kawecki C, Venisse L, Boulaftali Y, Christophe OD, Lenting PJ, Arocas V, de Raucourt E, Denis CV, Bouton MC 2019 • Blood • [pdf] Hemophilia A and B, diseases caused by the lack of factor VIII (FVIII) and factor IX (FIX) respectively, lead to… Read more »
A post-doctoral position is available for one year, in the first instance, in Pr. Jean-Michel Sallenave’s laboratory (see address below) in the INSERM Unit 1152 (Physiopathologie et Epidémiologie des maladies respiratoires). Starting date as early as February 2020. The successful candidate will have recently obtained a PhD in Immunology, and will have expertise in FACS technology and cell biology/molecular biology techniques. The project aims at… Read more »
Bronchodilation induced by PGE2 is impaired in Group-III pulmonary hypertension Ozen G, Benyahia C, Mani S, Boukais K, Silverstein AM, Bayles R, Nelsen AC, Castier Y, Danel C, Mal H, Clapp LH, Longrois D, Norel X 2019 • Br J Pharmacol • [pdf] BACKGROUND AND PURPOSE: In patients with pulmonary hypertension (PH) associated with lung disease and/or hypoxia (Group III), a reduction… Read more »
La société AMBIOTIS basée à Toulouse est reconnue par la communauté scientifique internationale, pour sa capacité unique à travailler sur la résolution de la réponse inflammatoire de manière innovante. La société travaille avec les industries Pharmaceutiques, Biotechnologiques, Cosmétiques et d’Aliments Santé. Nous vous proposons de travailler dans un environnement innovant, à la pointe de la technologie et en lien avec… Read more »
In issue 44 of the INSERM journal, an article is devoted to the Tridek-one startup whose 2 scientific co-founders are Giuseppina CALIGIURI and Antonino NICOLETTI who lead Team 1. Read the Article.
Véronique AROCAS a posté de nouveaux documents pour l’aide à la préparation de demandes APAFIS. Intranet->’General Interest Docs’.
Ticagrelor in Patients with Stable Coronary Disease and Diabetes Steg PG, Bhatt DL, Simon T, Fox K, Mehta SR, Harrington RA, Held C, Andersson M, Himmelmann A, Ridderstrale W, Leonsson-Zachrisson M, Liu Y, Opolski G, Zateyshchikov D, Ge J, Nicolau JC, Corbalan R, Cornel JH, Widimsky P, Leiter LA, Committee TS, Investigators 2019 • N Engl J Med • [pdf] BACKGROUND:… Read more »
Mitigation of monocyte driven thrombosis on cobalt chrome surfaces in contact with whole blood by thin film polar/hydrophobic/ionic polyurethane coatings Gossart A, Letourneur D, Gand A, Regnault V, Ben Mlouka MA, Cosette P, Pauthe E, Ollivier V, Santerre JP 2019 • Biomaterials • [pdf] Monocytes are active at the crossroads between inflammation and coagulation processes since they can secrete pro-inflammatory cytokines… Read more »
Giuseppina Caligiuri (Team 1) and Danilo Norata (University of Milan) present the content of a Cardiovascular Research spotlight issue focusing on immunometabolism. Link to issue. Aim of this Spotlight Issue is to present an overview of how changes in metabolic pathways of immune cells impact their function in the context of cardiovascular and metabolic diseases. Moreover, classical risk factors affect… Read more »
Mechanotransduction, immunoregulation, and metabolic functions of CD31 in cardiovascular pathophysiology Caligiuri G 2019 • Cardiovasc Res • [pdf] Biomechanical changes in the heart and vessels drive rapid and dynamic regulation of blood flow, a vital process for meeting the changing metabolic needs of the peripheral tissues at any given point in time. The fluid movement of the blood exerts haemodynamic stress… Read more »
The ISTH honored Martine Jandrot-Perrus (Team 6) amongst four other members with the Esteemed Career Award at the ISTH 2019 Congress Opening Ceremony. These awards are presented annually to individuals whose career contributions have significantly advanced the scientific community’s understanding of diseases and disorders that affect hemostasis. Their accomplishments are internationally regarded as exemplary models of research and mentoring excellence…. Read more »
Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab Voors-Pette C, Lebozec K, Dogterom P, Jullien L, Billiald P, Ferlan P, Renaud L, Favre-Bulle O, Avenard G, Machacek M, Pletan Y, Jandrot-Perrus M 2019 • Arterioscler Thromb Vasc Biol • [pdf] • [Editorial] Objective– ACT017 is a novel, first in class, therapeutic antibody to platelet GPVI… Read more »
Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus Li B, Aid-Launais R, Labour MN, Zenych A, Juenet M, Choqueux C, Ollivier V, Couture O, Letourneur D, Chauvierre C 2019 • Biomaterials • [pdf] Thrombotic diseases rarely cause symptoms until advanced stage and sudden death. Thus, early detection of thrombus by a widely spread imaging modality… Read more »
